Friocell

Stability & Environmental Chamber - Cooling, Freeze-Thaw, BOD

Applications

(ICH Q1A) Stability Testing
(ICH Q1B) Photostability Testing
Freeze-Thaw (EVO)
BOD-Water Testing (ECO)
Cooling Incubation
Shelf Life Testing
Material Testing

Overview

The FRIOCELL® is designed to create an exact reproduceable simulation of environmental conditions through precise temperature control and programmable cycles. FRIOCELL® environmental chambers are ideal for ICH Q1A stability and Q1B photostability testing, freeze-thaw testing, BOD water quality testing, shelf-life studies, and microbiology studies.

Scientific & Laboratory Brochure

FRIOCELL – Cooling, Freeze Thaw, BOD Test Chambers

Chamber Sizes & Construction

Patented forced air convection system moves air vertically and horizontally for precise temperature uniformity.

Friocell Chamber Sizes

  • 111 (4 ft³)
  • 222 (8 ft³)
  • 404 (14.3 ft³)
  • 707 (25 ft³)
  • 1212 (43 ft³)

Chamber Construction

The FRIOCELL® is equipped with a pharmaceutical grade AISI 304 stainless steel chamber with a double wall construction to prolong life expectancy. The inner chamber features a seamless, rounded corner design and is fully removable for easier cleaning and sterilization. The door of the chamber employs a patented 4-point closing system that seals the door to the chamber gasket and enables hands-free opening and closing.
  • AISI 304 stainless steel chamber – 316L stainless steel option available
  • Double wall chamber construction with 5 layers of insulation for more uniform internal chamber conditions
  • Removeable inner chamber with seamless, rounded corner design for easier cleaning & sterilization
  • 4-point closing system that seals the door to the chamber gasket – automatic or key door lock options availabe, door sensor and alarm option available
  • Inner glass door to view into the chamber
  • (2″) 50 mm stainless steel port – (1″) 25, (2″) 50, (4″) 100 mm access port options available
  • Shelf brackets that do not penetrate the chamber walls – brackets are molded into the inner chamber walls 2.8″ apart

Control Panel

FRIOCELL® incubators are offered with ECO and EVO control system options, each equipped with varying features to match your specific use case and budget. Through the use of fuzzy logic, the controllers can assess process data, such as operating temperature, chamber size, and other controlled elements. Based on the assessed data, the controller can make continuous adjustments to input values, such as heating intensity or cooling, to optimally regulate internal chamber conditions. Additionally, the controllers can quickly ramp up to the exact temperature set point without overshooting, minimizing the time required to meet set process parameters. The result is reduced overall cycle time, power consumption, and recovery times after opening the chamber door(s).

ECO

  • 3″ LCD display
  • Fuzzy logic enabled microprocessor
  • 9 programs each with up to 2 segments for varying loads and parameters up to 99 cycles
  • Real-time programming and cycling – optional temperature ramping settings
  • LED indicator of device operation
  • Constant monitoring of chamber conditions
  • USB device & flash port – (optional on 22 & 55 models)
  • RS 232 port
  • Optional Ethernet port
  • Delayed heating start & stop function
  • Digital safety thermostat
  • Acoustic and digital alarms
  • Keypad lock
  • optional integrated data logger for temperature and relative humidity measurement and recording

EVO

  • 5.7″ LCD color display – glove friendly touch screen
  • Fuzzy logic enabled microprocessor
  • 100 programs each with up to 100 segments for varying loads and parameters
  • Real-time control of temperature ramp settings, heating sequences, and cycling
  • Graphic display of cycle parameters
  • LED indicator of device operation
  • Constant monitoring of chamber conditions
  • USB port & SD card slot with Microsoft Excel formatted data storage
  • RS 232 port
  • Optional Ethernet port & WiFi connectivity
  • Delayed heating start & stop function
  • DIN 12880 digital safety thermostat
  • Acoustic and digital alarms
  • Multi-level secure user login compliant with FDA CFR 21 part 11
  • Data encryption compliant with FDA 21 CFR Part 11
  • Remote access

Lighting Options

The FRIOCELL® offers a wide range of lighting options to suit your specific application, including ICH Q1B Photostability. Available options for lighting placement, light sources, and intensity controls allows the FRIOCELL® to meet even the most demanding requirements for exposure lighting applications.

At a Glance:

  • Fluorescent UV/VIS lighting for ICH Q1B with programmable time and intensity (0-100%)
  • Fluorescent tubes or white LED lighting installed in the unit door or shelves
  • UV/VIS light sensors usable from 10°C up to 70°C