Products / Stability & Environmental Chambers / Climacell
Applications
(ICH Q1A) Stability Testing
(ICH Q1B) Photostability Testing
Cooling Incubation
Shelf Life Testing
Freeze-Thaw
Material Testing
Overview
CLIMACELL® stability and environmental chambers are designed to create exact reproducible simulations of a wide range of environmental conditions through precise control of temperature and humidity within the chamber. CLIMACELL® incubators are ideal for shelf life studies, as well as ICH Q1A stability and ICH Q1B photostability studies when equipped with the EVO advanced controller and LED or Fluorescent lighting options.
ECO Standard Controller
Compliant with ICH Q1A Guidelines
ECO Digital Controller Enabled with Fuzzy Logic Algorithm – ensures accurate temperatures without overshooting the set point – flexible and repeatable cycles
FDA CFR 21 Part 11 Compliant for electronic data storage with addition of Warmcomm 4.0F software
Patented Forced Air Convection System moves air vertically and horizontally for precise temperature uniformity
Temperature Range: 0°C up to 100°C (optional -10°C min. temp) with humidity: 10°C up to 95°C
Humidity Range: 10% – 95%, controlled in 1% increments
Active dehumidification for precise humidity control as uniform as 2.5%
Active dehumidification for precise humidity control as uniform as 2.5%
Water tank with pump for water supply included with all CLIMACELL® chambers
Wastewater vessel water pump to remove condensate
Power: 230V 60Hz
CE, UL, CSA listed
EVO Advanced Controller
Compliant with ICH Q1A & Q1B guidelines
EVO Digital Controller Enabled with Fuzzy Logic Algorithm – (see control panel section below for controller features)
FDA CFR 21 Part 11 Compliant for electronic data storage with addition of Warmcomm 4.0F software
Patented Forced Air Convection System moves air vertically and horizontally for precise temperature uniformity
Temperature Range: 0°C up to 100°C (optional -20°C min. temp) with humidity: 10°C up to 95°C
Sterilization Cycle: 160°C
Humidity Range: 10% – 95%, controlled in 1% increments
Active dehumidification for precise humidity control as uniform as 2.5%
Active dehumidification for precise humidity control as uniform as 2.5%
Water tank with pump for water supply included with all CLIMACELL chambers®
Wastewater vessel water pump to remove condensate
ICH Q1B Lighting: UV/VIS shelf and door lighting – *LED or flourescent tube, fully programmable light intensity, microprocessor dimming 0% – 100%
Power: 230V 60Hz
CE, UL, CSA listed
Options
SHELVING & TRAYS
- Stainless steel wire shelf
- Stainless steel perforated shelf
- Suspension system for hanging samples from the ceiling of the chamber
- Stainless steel exterior
- 316L stainless steel chamber
- Adjustable feet or casters with smooth travel and extendable leveling feet
- Window with 3 layers of insulating glass for observation of samples inside the chamber – complimented by interior light with mechanical switch
- Interior light – heat resistant with mechanical switch or an electronic switch that is automatically activated when the door opens
- Waterproof 115V electrical socket inside the chamber
- External printer Functionality
- Oxygen control 1% – 19%
- PT 100 flexible sensor
- Inert gas or aeration connection
- Lighting control, VIS
- Lighting control, UV
- IQ/OQ validation documentation with temperature mapping – DIN 12880
- Warmcomm Software – FDA 21 CFR part 11 compliant
- Building Management System monitoring alarm
- Region specific electrical plug
Chamber Sizes & Construction
Patented forced air convection system moves air vertically and horizontally for precise temperature uniformity.
Climacell Chamber Sizes
- 111 (4 ft³)
- 222 (8 ft³)
- 404 (14.3 ft³)
- 707 (25 ft³)
- 1212 (43 ft³)
Chamber Construction
The CLIMACELL® is equipped with a pharmaceutical grade AISI 304 stainless steel chamber with a double wall construction to prolong life expectancy. The inner chamber features a seamless, rounded corner design and is fully removable for easier cleaning and sterilization. The door of the chamber employs a patented 4-point closing system that seals the door to the chamber gasket and enables hands-free opening and closing.
- AISI 304 stainless steel chamber – 316L stainless steel option available
- Double wall chamber construction with 5 layers of insulation for more uniform internal chamber conditions
- Removeable inner chamber with seamless, rounded corner design for easier cleaning & sterilization
- 4-point closing system that seals the door to the chamber gasket – automatic or key door lock options availabe, door sensor and alarm option available
- Inner glass door to view into the chamber
- (2″) 50 mm stainless steel port – (1″) 25, (2″) 50, (4″) 100 mm access port options available
- Shelf brackets that do not penetrate the chamber walls – brackets are molded into the inner chamber walls 2.8″ apart
Control Panel
CLIMACELL® stability and enviromental chambers are offered with ECO and EVO control system options, each equipped with varying features to match your specific use case and budget. Through the use of fuzzy logic, the controllers can assess process data, such as operating temperature, chamber size, and other controlled elements. Based on the assessed data, the controller can make continuous adjustments to input values, such as heating intensity or cooling, to optimally regulate internal chamber conditions. Additionally, the controllers can quickly ramp up to the exact temperature set point without overshooting, minimizing the time required to meet set process parameters. The result is reduced overall cycle time, power consumption, and recovery times after opening the chamber door(s).
ECO
- 3″ LCD display
- Fuzzy logic enabled microprocessor
- 9 programs each with up to 8 segments for varying loads and parameters up to 99 cycles
- Real-time programming and cycling – optional temperature ramping settings
- LED indicator of device operation
- Constant monitoring of chamber conditions
- USB device & flash port – (optional on 22 & 55 models)
- RS 232 port
- Optional Ethernet port
- Delayed heating start & stop function
- Digital safety thermostat
- Acoustic and digital alarms
- Keypad lock
- optional integrated data logger for temperature and relative humidity measurement and recording
EVO
- 5.7″ LCD color display – glove friendly touch screen
- Fuzzy logic enabled microprocessor
- 100 programs each with up to 100 segments for varying loads and parameters
- Real-time control of temperature ramp settings, heating sequences, and cycling
- Graphic display of cycle parameters
- LED indicator of device operation
- Constant monitoring of chamber conditions
- USB port & SD card slot with Microsoft Excel formatted data storage
- RS 232 port
- Optional Ethernet port & WiFi connectivity
- Delayed heating start & stop function
- DIN 12880 digital safety thermostat
- Acoustic and digital alarms
- Multi-level secure user authentication – FDA CFR 21 part 11 compliant
- Remote access
Lighting Options
The CLIMACELL® offers a wide range of lighting options to suit your specific application, including ICH Q1B photostability. Available options for lighting placement, light sources, and intensity controls allows the CLIMACELL® to meet even the most demanding requirements for exposure lighting applications.
At a Glance:
- Fluorescent UV/VIS lighting for ICH Q1B with programmable time and intensity (0-100%)
- Fluorescent tubes or white LED lighting installed in the unit door or shelves
- UV/VIS light sensors usable from 10°C up to 70°C
Previous
Next