BMT USA depyrogenation ovens provide efficient dry heat sterilization for the complete destruction of microorganisms and endotoxins. Ideal for empty glassware, including ampoules, vials, and injection bottles, as well as stainless steel tools and select closed containers with low-aqueous liquids or powders.
Fully cGMP-compliant, the ovens maintain ISO 14644-1 Class 5 conditions up to 280 °C and Class 7 up to 300 °C throughout the entire cycle without temperature ramping. This performance is enabled by a proven double-sealed chamber and unique filter suspension system. Environmentally safe and customizable, each unit can be tailored to your specific chamber size and capacity requirements.
A depyrogenation oven is a critical piece of equipment used in the pharmaceutical and biotech industries to remove contaminates from empty glass or metal containers through exposure to intense dry heat, typically ranging from 260°C to 300°C, for a controlled duration. This process effectively deactivates and destroys pyrogens, which are fever-inducing contaminants, ensuring the containers meet stringent safety and quality standards for drug manufacturing.
BMT USA depyrogenation ovens are primarily used to sterilize empty glass and metal containers, including ampoules, injection bottles, vials, and stainless steel equipment. Other applications include the sterilization of closed containers with low aqueous liquids and powder medicaments.
In general, a clean room is an enclosed space with equipment that controls the amount of particulate matter in the air by using air pressure and filters. ISO 14644-1 is a classification for clean rooms regulating the maximum particulate count per m3 as specified in the air cleanliness class. BMT USA depyrogenation ovens achieve ISO 14644-1 Class 5 and Class 7 thanks to a unique chamber construction and filter suspension system.
BMT USA offers custom chamber sizes to meet your specific capacity requirements. Please contact us to discuss your size requirements.
BMT USA offers custom stainless steel transfer trolleys, mobile racks, wire trays and cassettes to compliment any of our depyrogenation oven models.
Mobile racks are available with fixed or removable tray supports with adjustable spacing to match your load configuration. The mobile racks are also equipped with specialized wheels to withstand high temperatures without the need for lubrication.
BMT USA depyrogenation ovens include a standard 1-year warranty on parts and labor. Optional extended warranties for parts and labor are also available.
